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Amyloid Toxicity Inhibitor Peptide 11
| Overview | |
|---|---|
| Description | Amyloid toxicity inhibitor peptide 11 is composed of hydrophilic and hydrophobic amino acids. The positively charged unprotected N-terminus allows it to interact with negatively charged C-terminus of b-amyloid 1 to 40. It was shown that this peptide is effective in blocking fibrillization of transmembrane peptide derived from glycophorin A containing a GxMxG motif. Glycophorin sequence can form fibrils with a cross b-structure as in b-amyloid. This peptide inhibits fibrillization by binding to the surface of the beta sheet. |
| Sequence | RGTFEGKF-NH2 |
| Sequence (3 Letter) | H-Arg-Gly-Thr-Phe-Glu-Gly-Lys-Phe-NH2 |
| Molecular Weight | 940.1 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Sato, T. et al. Biochem. 45, 5509 (2006).
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InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.