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Tat - GluR23Y, scrambled
YGRKKRRQRRRVYKYGGYNE
| Overview | |
|---|---|
| Description | Tat-Glur23Y, scrambled is a control peptide. The synthetic peptide (Tat-Glur23Y), containing tyrosine residues, blocks phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. However, the scrambled version does not have blockade properties. Previous studies show that Tat-Glur23Y, scrambled increase stress levels in mice, while Tat-Glur23Y reduces stress when administered. |
| Sequence | YGRKKRRQRRRVYKYGGYNE |
| Sequence (3 Letter) | H - Tyr - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Val - Tyr - Lys - Tyr - Gly - Gly - Tyr - Asn - Glu - OH |
| Molecular Weight | 2634 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Dalton, G. et al. Neuropsychopharma. 33, 2416 (2008); Kim, J. et al. PNAS 104, 20955 (2007).
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