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Tat - GluR23Y
YGRKKRRQRRRYKEGYNVYG
| Overview | |
|---|---|
| Description | The synthetic peptide (Tat-Glur23Y) contains tyrosine residues that blocks phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. Previous research shows that Tat-Glur23Y blocks regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus. |
| Sequence | YGRKKRRQRRRYKEGYNVYG |
| Sequence (3 Letter) | H - Tyr - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Tyr - Lys - Glu - Gly - Tyr - Asn - Val - Tyr - Gly - OH |
| Molecular Weight | 2634 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Dalton, G. et al. Neuropsychopharma. 33, 2416 (2008); Kim, J. et al. PNAS 104, 20955 (2007).
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.