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Cys(Npys) - (D - Arg)9
C(Npys)rrrrrrrrr - NH2
| Overview | |
|---|---|
| Description | This is a peptide comprising of 9 D-Arginine residues and is synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group protects cysteine. This kind of modification has been used to render this peptide as a carrier peptide applicable in conjugation and cell permable studies. The S(Npys) group of this cysteine-containing 9R is capable of reacting selectively with the free thiol group of another cysteine-containing peptide to form an unsymmetrical disulfide bond. In a bioconjugation study, D-Arg-C(Nyps) was shown to mediate delivery of TALEN proteins into mammalian cells. |
| Sequence | C(Npys)rrrrrrrrr-NH2 |
| Sequence (3 Letter) | H - Cys(Npys) - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - NH2 |
| Molecular Weight | 1680.1 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Liu J. et al. PLOS One. 9(1):e85755 (2014).
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