![[Lys(Ac)373] - p53 (368 - 393), p53 K373(Ac), biotin - labeled, human](/media/com_eshop/products/resized/prod_150x150-500x500.png "[Lys(Ac)373] - p53 (368 - 393), p53 K373(Ac), biotin - labeled, human")
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[Lys(Ac)373] - p53 (368 - 393), p53 K373(Ac), biotin - labeled, human
| Overview | |
|---|---|
| Description | This peptide is tumor suppressor protein, p53 (368-393). There is a biotinylated lyine followed by a GG linker at the N-terminal and an acetylated lysine at lysine 373. Activation of the p53 protein results in the transcription of antiproliferative proteins and induction of apoptosis. The p53 tumor suppressor is a principal mediator of growth arrest, senescence, and apoptosis in response to a broad array of cellular damage. |
| Sequence | Biotin-KGGHLKSK-K(Ac)-GQSTSRHKKLMFKTEGPDSD-NH2 |
| Sequence (3 Letter) | Biotin-Lys-Gly-Gly-His-Leu-Lys-Ser-Lys-Lys(Ac)-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2 |
| Molecular Weight | 3481 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Kanovsky, M. et al. Proc Natl Acad Sci 98, 12438 (2001).
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