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Phe-Met-Arg-Phe, amide
| Overview | |
|---|---|
| Synonyms | F-M-R-F;-amide; Phe-Met-Arg-Phe amideMolluscan cardioexcitatory neuropeptide |
| Description | FMRF-amide belongs to Molluscan Cardioexcitatory Neuropeptide. This peptide appears to localize with neuropeptide Y in some regions of the brain. FMRF-amide inhibits Na+-Ca2+ exchange in cardiac sarcolemma vesicles. The neuropeptide FMRF-amide stimulated enzyme activity 7- to 8-fold (EC50, 1 mM) via receptors that were pharmacologically distinct from those for dopamine and serotonin. FMRF- amide augmented cyclic AMP levels in slices of gill tissue with a time course similar to that for adenylate cyclase activation. |
| Cas No | 64190-70-1 |
| Sequence | {PHE}{MET}{ARG}{PHE}-NH2 |
| Sequence Shortening | FMRF-NH2 |
| Molecular Formula | C29H42N8O4S1 |
| C Terminal | NH2 |
| Molecular Weight | 598.76 |
| Properties | |
| Purity | > 95% |
| Solubility | Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Gmp Flag | 0 |
| Storage | Store at -20°C |
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