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Fibrinogen Binding Inhibitor Peptide
| Overview | |
|---|---|
| Synonyms | Fibrinogen Binding Inhibitor |
| Description | Fibrinogen Binding Inhibitor Peptide, a synthetic dodecapeptide, represents the specific platelet receptor recognition site of the human fibrinogen g-chain (residues 400-411). It is also a potent inhibitor of the binding of fibrinogen, fibronectin, and von Willebrand factor to thrombin- or ADP-stimulated platelets. Fibrinogen Binding Inhibitor Peptide has been used in studying phosphorylation processes associated with platelet activation. |
| Cas No | 89105-94-2 |
| Sequence | {HIS}{HIS}{LEU}{GLY}{GLY}{ALA}{LYS}{GLN}{ALA}{GLY}{ASP}{VAL} |
| Sequence Shortening | HHLGGAKQAGDV |
| Molecular Formula | C50H80N18O16 |
| Molecular Weight | 1189.3 |
| Properties | |
| Purity | > 95% |
| Solubility | Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Gmp Flag | 0 |
| Storage | Before using, store the peptide in the DRY form at 0-5°C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions. |
| Note | In activated platelets, single γ 400-411 sequence is no longer required for initiation of adhesion but becomes sufficient for firm adhesion. In contrast to the binding of whole fibrinogen, binding of fragment 400-411 does not lead to tyrosine phosphorylation for platelet proteins. |
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.