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Overview | |
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Synonyms | LH-RH, salmonLuteinizing hormone releasing hormone, salmon |
Description | LH-RH is a hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions. It has been assumed, usually with good reason, that D-amino acids with large aromatic side-chains must be present in position 6 of both LH-RH superagonists and antagonists for the highest levels of biological activity to be reached. However, using one of a recent generation of potent lH-RH inhibitory analogs as a model, we have found that the insertion of D-lysine or, better still, D-arginine in this position results in greater antiovulatory activity in the rat over corresponding D-phenylalanine6- and D-tryptophan6-analogs. |
Cas No | 86073-88-3 |
Sequence | {pGLU}{HIS}{TRP}{SER}{TYR}{GLY}{TRP}{LEU}{PRO}{GLY} |
Molecular Formula | C60H73N15O13 |
C Terminal | NH2 |
Molecular Weight | 1212.31 |
Properties | |
Purity | > 95% |
Gmp Flag | 0 |
Storage | Store at -20°C. |
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.