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IV9 (476 - 484), HIV - 1 RT Epitope
| Overview | |
|---|---|
| Description | This is a reverse transcriptase (RT) epitope (Pol residues 476-484). Within HIV-1 RT the peptide appears to be the dominant HLA A*0201-restricted epitope. Was used to investigate possible mechanisms behind HIV-1 escape from CTL. IV9 is the actual epitope processed and presented in HIV-1-infected cell lines |
| Sequence | ILKEPVHGV |
| Sequence (3 Letter) | H-Ile-Leu-Lys-Glu-Pro-Val-His-Gly-Val-OH |
| Molecular Weight | 991.2 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Ref: Sewell, A. et al. The Journal of Immunology 162, 7075 (1999); Jamieson, B. et al. The Journal of Immunology 171, 5372 (2003); Ref: Brander, C. et al. J. Clin. Invest 101, 2559 (1998); Goulder,P. et al. J. Exp. Med 185, 1423 (1997)
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