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S3 Fragment, ADF/cofilin
MASGVMVSDDVVKVFN
| Overview | |
|---|---|
| Description | This peptide contains the unique amino-terminal phosphorylation site of Xenopus ADF/cofilin, the LIM kinase (LIMK) phosphorylation site. LIMK1 is a key regulator of the actin cytoskeleton through its phosphorylation of ADF/cofilin at serine-3 for inactivation. This peptide is a fragment of the S3 peptide containing the serine-3 sequence of ADF/cofilin that has been widely used as an effective competitive inhibitor of LIMK1. |
| Sequence | MASGVMVSDDVVKVFN |
| Sequence (3 Letter) | H - Met - Ala - Ser - Gly - Val - Met - Val - Ser - Asp - Asp - Val - Val - Lys - Val - Phe - Asn - OH |
| Molecular Weight | 1698 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Wen, Z. et al. J. Cell Biol. 178, 107 (2007).
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