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delta PKC (8 - 17); PKC d Inhibitor
SFNSYELGSL
| Overview | |
|---|---|
| Description | This peptide is derived from the V1 domain of protein kinase C (PKC)d. It inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Inhibition of PKCd reduces ischemia damage in cardiac and cerebral cells, induces proliferation of fibroblasts, and inhibits graft coronary artery disease in mice. |
| Sequence | SFNSYELGSL |
| Sequence (3 Letter) | H - Ser - Phe - Asn - Ser - Tyr - Glu - Leu - Gly - Ser - Leu - OH |
| Molecular Weight | 1116.2 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Bright, R. et al. J Neurosci 24, 6880 (2004). Tanaka, M. et al. Circulation 110, 194 (2004). Braun, M and D. Mochly-Rosen. J Mol Cell Cardiol 35 895 (2003). Chen, L. et al. Proc Natl Acad Sci USA 98, 11114 (2001).
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