![[pThr11] - Histone H3(1 - 21) - GGK(Biotin), H3pT11, biotin - labeled](/media/com_eshop/products/resized/prod_150x150-500x500.png "[pThr11] - Histone H3(1 - 21) - GGK(Biotin), H3pT11, biotin - labeled")
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[pThr11] - Histone H3(1 - 21) - GGK(Biotin), H3pT11, biotin - labeled
| Overview | |
|---|---|
| Description | This peptide is histone H3 amino acid residues 1 to 21. It is phosphorylated at Thr-11 with a C-terminal GG linker, followed by a biotinylated lysine. The modification of Thr-11 via phosphorylation is processed by a number of enzymes, including protein kinase C-related kinase 1 (PRK1) and Serine/threonine-protein kinase Chk1. This has many important functions, such as the establishment of a novel chromatin marker for transcriptional regulation, and the regulation of DNA-damage induced transcriptional repression. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form. |
| Sequence | ARTKQTARKS-pT-GGKAPRKQLAGG-K(Biotin)-NH2 |
| Sequence (3 Letter) | H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-pThr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-NH2 |
| Molecular Weight | 2802.2 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Metzger, E. et al. Nat Cell Biol 10, 53 (2010); Shimada, M. et al. Cell 132, 221 (2008).
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.