![[Lys(Ac)56] - Histone H3 (44 - 63) [Lys(Ac)56] - Histone H3 (44 - 63)](/media/com_eshop/products/resized/prod_150x150-230x230.png)
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Overview | |
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Description | This peptide is histone H3 (44-63) with acetylation at Lys56. Lys56 acetylation occurs during premeiotic and mitotic S phases and persists through DNA damage repair and is catalyzed by the Rtt109-Vps75 histone acetyltransferase (HAT) complex. A deficiency of acetylated Lys56 in histone H3 is implicated in spontaneous chromosome breaks during mitosis, suggesting that this modification is important for replisome integrity and DNA replication. |
Sequence | GTVALREIRRYQ-K(Ac)-STELLIR |
Sequence (3 Letter) | H-Gly-Thr-Val-Ala-Leu-Arg-Glu-Ile-Arg-Arg-Tyr-Gln-Lys(Ac)-Ser-Thr-Glu-Leu-Leu-Ile-Arg-OH |
Molecular Weight | 2444.9 |
Properties | |
Purity | > 95% By HPLC |
Storage | Store at -20 °C, cap vial tightly at all times. |
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