![[Lys(Ac)5] - Histone H4 (1 - 21) - GGK(Biotin), H4K5(Ac), biotin - labeled](/media/com_eshop/products/resized/prod_150x150-500x500.png "[Lys(Ac)5] - Histone H4 (1 - 21) - GGK(Biotin), H4K5(Ac), biotin - labeled")
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[Lys(Ac)5] - Histone H4 (1 - 21) - GGK(Biotin), H4K5(Ac), biotin - labeled
| Overview | |
|---|---|
| Description | This peptide is histone H4 amino acids 1 to 21, acetylated at Lys-5 and at the N-terminus. This peptide also contains a C-terminal GG linker, followed by a biotinylated lysine. The acetylation of histone H4 causes structural changes that play a crucial role in amplifying the binding of transcription factors to specific recognition sites within the nucleosome. |
| Sequence | Ac-SGRG-K(Ac)-GGKGLGKGGAKRHRKVGG-K(Biotin) |
| Sequence (3 Letter) | Ac-Ser-Gly-Arg-Gly-Lys(Ac)-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val-Gly-Gly-Lys(Biotin)-OH |
| Molecular Weight | 2644.1 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Vettes-Dadey, M. et al. EMBO J 15, 10 (1996).
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