![[Cit3] - Histone H4 (1 - 23) - GGK(Biotin)](/media/com_eshop/products/resized/prod_150x150-500x500.png "[Cit3] - Histone H4 (1 - 23) - GGK(Biotin)")
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[Cit3] - Histone H4 (1 - 23) - GGK(Biotin)
| Overview | |
|---|---|
| Description | This peptide is histone H4 (1-23) with deimination at Arg3. It contains a C-terminal GGK linker with biotinylation on the side chain of this Lys. Deimination of Arg3 to Cit is carried out by peptidylarginine deiminase (PADI)-4. Although the function of deimination is not clearly known, it has been shown to inhibit Arg methylation and repress nuclear hormone receptor-dependent gene activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form. |
| Sequence | SG-Cit-GKGGKGLGKGGAKRHRKVLRGG-K(Biotin) |
| Sequence (3 Letter) | H-Ser-Gly-Cit-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val-Leu-Arg-Gly-Gly-Lys(Biotin)-OH |
| Molecular Weight | 2830.4 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Hagiawara, T. et al. Biochem 44, 5827 (2005).
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