Call Now: +1 858 800 3101 Email: info@innopep.com
Shopping Cart
0 Item(s) - $0.00
Your shopping cart is empty!
IKKγ NEMO Binding Domain (NBD) Inhibitory Peptide
DRQIKIWFQNRRMKWKKTALDWSWLQTE
| Overview | |
|---|---|
| Description | A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB. |
| Sequence | DRQIKIWFQNRRMKWKKTALDWSWLQTE |
| Sequence (3 Letter) | H - Asp - Arg - Gln - Ile - Lys - Ile - Trp - Phe - Gln - Asn - Arg - Arg - Met - Lys - Trp - Lys - Lys - Thr - Ala - Leu - Asp - Trp - Ser - Trp - Leu - Gln - Thr - Glu - OH |
| Molecular Weight | 3693.3 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Ref: Paria, B. et al. J. Biol. Chem. 278, 37195 (2003); Tian, M. et al. Blood May 2005(10.1182/blood-2004-04-1248); Bharti, A. Blood 101, 1053 (2003).
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.