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Neurogranin (48 - 76), human
| Overview | |
|---|---|
| Description | Neurogranin is a post synaptic protein that is expressed in dendritic cytoplasm. It modulates calcium-mediated signaling pathways and plays critical role in synaptic plasticity. Recently Neurogranin (48-76) was identified as a major neurogranin peptide fragment in human brain and it was found that patients with Alzheimer €™s Disease have elevated levels of Neurogranin (48-76) in cerebrospinal fluid. |
| Sequence | SGERGRKGPGPGGPGGAGVARGGAGGGPS |
| Sequence (3 Letter) | Ser - Gly - Glu - Arg - Gly - Arg - Lys - Gly - Pro - Gly - Pro - Gly - Gly - Pro - Gly - Gly - Ala - Gly - Val - Ala - Arg - Gly - Gly - Ala - Gly - Gly - Gly - Pro - Ser - OH |
| Molecular Weight | 2417.8 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | This peptide is shipped at ambient temperature. Upon receipt, store lyophilized peptide at €“20 °C or lower. Reconstituted peptide can be aliquoted and stored at €“20 °C or lower. |
1. De Vos A., et.al., Alzh and Dement 4, 1-9 (2015)
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