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NY - ESO - 1 (87 - 111)
LLEFYLAMPFATPMEAELARRSLAQ
| Overview | |
|---|---|
| Description | This is amino acids 81 to 111 fragment of the NY-ESO-1. The NY-ESO-1 antigen is expressed by many tumors of different histological types (including breast, prostate, lung, and melanoma) and by male germline cells, but not by other normal tissues. NY-ESO-1 encodes MHC class I- and class II-restricted peptides expressed by a diverse range of cancers and recognized by T cells. This peptide is pan-MHC class II-restricted sequence that is capable of binding to multiple HLA-DR and HLA-DP4 molecules, including HLA-DRB1*0101, 0401, 0701, and 1101 and HLA-DPB1*0401 and 0402 molecules. |
| Sequence | LLEFYLAMPFATPMEAELARRSLAQ |
| Sequence (3 Letter) | H - Leu - Leu - Glu - Phe - Tyr - Leu - Ala - Met - Pro - Phe - Ala - Thr - Pro - Met - Glu - Ala - Glu - Leu - Ala - Arg - Arg - Ser - Leu - Ala - Gln - OH |
| Molecular Weight | 2869.4 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Mandic, M. et al. J. Immunol. 174, 1751 (2005).
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