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Product Code: 3354-0100

Price: $106.00

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Overview
Description This is amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). It is one of the first fragments of this islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with p524 €“543 increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells.
Sequence SRLSKVAPVIKARMMEYGTT
Sequence (3 Letter) H - Ser - Arg - Leu - Ser - Lys - Val - Ala - Pro - Val - Ile - Lys - Ala - Arg - Met - Met - Glu - Tyr - Gly - Thr - Thr - OH
Molecular Weight 2238.7
Properties
Purity % Peak Area By HPLC ≥ 95%
Storage -20 °C
Quinn, A. et al. J. Immunol. 166, 2982 (2001); Dai, Y. et al. J. Immunol. 175, 3621 (2005).

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InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.

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