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Melan - A/MART - 1 (27 - 35)
AAGIGILTV
| Overview | |
|---|---|
| Description | Melan-A is a melanocyte differentiation antigen recognized by cytotoxic T lymphocytes. This sequence is a naturally presented Melan-A/MART-1 nonamer peptide. The Melan-A/MART-1 gene is expressed by normal melanocytes, as well as by most fresh melanoma samples and melanoma cell lines. This peptide appears to be a very common immunogenic epitope for HLA-A2-restricted melanoma-specific tumor-infiltrating lymphocytes (TIL) and may be useful for the development of immunotherapeutic strategies. |
| Sequence | AAGIGILTV |
| Sequence (3 Letter) | H - Ala - Ala - Gly - Ile - Gly - Ile - Leu - Thr - Val - OH |
| Molecular Weight | 814.6 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Ref: Kawakami, Y. et al. J. Exp. Med 180, 347 (1994); Schneider, J. et al. Int. J. Cancer 75, 451 (1998).
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