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Substance P (8 - 11)
| Overview | |
|---|---|
| Description | Substance P (SP) is an important neuropeptide that has been implicated in several physiological processes. This SP fragment 8 to 11 amino acids was used in the healing of corneal epithelial wounds study. The combination of FGLM-NH2 and IGF-1 promotes corneal epithelial wound healing in diabetic rats, suggesting that this kind of treatment might prove effective in humans with diabetic keratopathy. Administration of eyedrops containing both FGLM €“NH2 and SSSR is effective for the treatment of persistent epithelial defects in individuals with neurotrophic keratopathy. |
| Sequence | FGLM-NH2 |
| Sequence (3 Letter) | H-Phe-Gly-Leu-Met-NH2 |
| Molecular Weight | 465.6 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Nakamura, M. et al. Diabetologia 46, 839 (2003); Yamada, et al. Invest. Ophthalmol. Vis. Sci. 47, 5018 (2006).
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