![MARCKS Protein (154 - 165) [KKRFSFKKSFKL], 5 - TMR labeled](/media/com_eshop/products/resized/prod_150x150-500x500.png "MARCKS Protein (154 - 165) [KKRFSFKKSFKL], 5 - TMR labeled")
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MARCKS Protein (154 - 165) [KKRFSFKKSFKL], 5 - TMR labeled
| Overview | |
|---|---|
| Description | Peptide sequence KKRFSFKKSFKL is derived from amino acid residues 154 €“165 of myristoylated alanine-rich C-kinase substrate (MARCKS) protein phosphorylation site domain (PSD). It retains the first two of the four serine residues in the PSD. This peptide is proven to be a generic substrate for protein kinase C (including PKCα and β, naturally-occurring PKC δ, ε, and θ, as well as atypical PKC ξ) at Ser5 and Ser9, even though atypical PKCs do not utilize intact MARCKS as a substrate. |
| Sequence | 5-TMR-KKRFSFKKSFKL |
| Sequence (3 Letter) | 5-TMR-Lys-Lys-Arg-Phe-Ser-Phe-Lys-Lys-Ser-Phe-Lys-Leu-OH |
| Molecular Weight | 1956.4 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Ref: Irie, K. et al. Pharmacol. Ther. 93, 271 (2002); Uberall, F. et al. J. Biol. Chem. 272, 4072 (1997); Blackshear, P. J. Biol. Chem. 268, 1501 (1993).
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