Call Now: +1 858 800 3101 Email: info@innopep.com
Shopping Cart
0 Item(s) - $0.00
Your shopping cart is empty!
Gamma - Fibrinogen (377 - 395)
YSMKETTMKIIPFNRLSIG
| Overview | |
|---|---|
| Description | This fibrinogen-derived inhibitory peptide attenuates microglia activation and suppresses relapsing paralysis in multiple sclerosis (MS). Fibrinogen is a regulator of microglia activation and interaction of fibrinogen with the microglia integrin receptor Mac-1. Because blocking fibrinogen €“Mac-1 interactions affects the pro-inflammatory but not the pro-coagulant properties of fibrinogen, targeting this gamma- fibrinogen epitope could represent a potential therapeutic strategy for MS and other neuroinflammatory diseases associated with blood-brain barrier disruption and microglia activation. |
| Sequence | YSMKETTMKIIPFNRLSIG |
| Sequence (3 Letter) | H - Tyr - Ser - Met - Lys - Glu - Thr - Thr - Met - Lys - Ile - Ile - Pro - Phe - Asn - Arg - Leu - Ser - Ile - Gly - OH |
| Molecular Weight | 2229.7 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Adams, R. et al. J. Exp. Med. Published online 5 March 2007 doi:10.1084/jem.20061931
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.