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Peptide P60
| Overview | |
|---|---|
| Description | Peptide P60 has demonstrated the potential to inhibit the immunosuppressive activity of murine and human-derived regulatory T-cells (Tregs). It enhances the effector T-cell stimulation in vitro by binding to regulatory T-cells specific forkhead/winged helix transcription factor 3 (FOXP3). Peptide P60 can enter the cells to inhibit FOXP3 nuclear translocation and activity on other transcription factors. In vitro, peptide P60 (100 uM) inhibited murine and human-derived Treg and improved effector T cell stimulation. |
| Sequence | RDFQSFRKMWPFFAM |
| Sequence (3 Letter) | H-Arg-Asp-Phe-Gln-Ser-Phe-Arg-Lys-Met-Trp-Pro-Phe-Phe-Ala-Met-OH |
| Molecular Weight | 1994.34 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.