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Transportan
GWTLNSAGYLLGKINLKALAALAKKIL
| Overview | |
|---|---|
| Description | This peptide is Transportan (TP), a 27 amino acids (aa) long chimeric peptide containing 12 aa from the amino-terminal part of the neuropeptide galanin and the 14 aa long mastoparan (Vespula lewisii wasp venom), connected via a lysine residue. TP reveals some characteristic features of both galanin and mastoparan since it inhibits the binding of galanin to GALR-1 receptor as well as modulates the activity of G proteins due to the inhibition of GTPase activity. |
| Sequence | GWTLNSAGYLLGKINLKALAALAKKIL |
| Sequence (3 Letter) | Gly - Trp - Thr - Leu - Asn - Ser - Ala - Gly - Tyr - Leu - Leu - Gly - Lys - Ile - Asn - Leu - Lys - Ala - Leu - Ala - Ala - Leu - Ala - Lys - Lys - Ile - Leu |
| Molecular Weight | 2841.5 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Wierzbicki PM. Et al Folia Histochemica et Cytobiologica. 52(4):270-280 (2014).
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