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Protease - Activated Receptor - 2, PAR - 2 Agonist, amide NEW
2 - Furoyl - LIGRLO - NH2
| Overview | |
|---|---|
| Description | The peptide 2-furoyl-LIGRLO-NH2 showed higher potency and receptor selectivity for in vitro assays than other PAR-2-activating peptides. 2-Furoyl-LIGRLO-NH2 peptide was equally or more potent than SLIGRL-NH2 for increasing intracellular calcium in cultured human and rat PAR-2-expressing cells and significantly more potent than SLIGRL-NH2 in assays of tissue PAR-2 activity. |
| Sequence | 2-Furoyl-LIGRLO-NH2 |
| Sequence (3 Letter) | 2 - Furoyl - Leu - Ile - Gly - Arg - Leu - Orn - NH2 |
| Molecular Weight | 778 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
McGuire, JJ. et al. J Pharmacol Exp Ther 309, 1124 (2004).
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