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MUC5AC - 3/13
GT - T* - PSPVPTTST - T* - SAP
| Overview | |
|---|---|
| Description | This glycopeptide is a MUC5AC peptide with two sites (Thr3 and Thr13) labeled with GalNAc, where the asterisk denotes GalNAc-modified residues. Mucin type O-linked glycosylation is initiated by the action of a family of UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferases (ppGaNTase), which catalyze the transfer of GalNAc from the nucleotide sugar UDP-GalNAc to the hydroxyl group of either serine or threonine. |
| Sequence | GT-T*-PSPVPTTST-T*-SAP |
| Sequence (3 Letter) | H - Gly - Thr - Thr* - Pro - Ser - Pro - Val - Pro - Thr - Thr - Ser - Thr - Thr* - Ser - Ala - Pro - OH (Thr* labeled with GalNAc) |
| Molecular Weight | 1907.6 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Ten Hagen, K. et al. J. Biol. Chem. 277, 22616 (2002).
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