![[Trp63, 64] - C3a (63 - 77)<br>WWGKKYRASKLGLAR](/media/com_eshop/products/resized/prod_150x150-500x500.png "[Trp63, 64] - C3a (63 - 77)<br>WWGKKYRASKLGLAR")
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[Trp63, 64] - C3a (63 - 77)
WWGKKYRASKLGLAR
| Overview | |
|---|---|
| Description | This peptide, which is a C-terminal analogue of the complement factor C3a, acts as an agonist to the C3a receptor. It is derived from the fifteen C-terminal residues (6-77) of C3a. In in vitro studies, both C 3a and this peptide have been shown to selectively bind to C3aRs and induce degranulation of C3aR-transfeted RBL-2H3 cells. There was also a rapid, transient and concentration-dependent hypertensive response observed in rats when infused intravenously with C3a and this peptide. |
| Sequence | WWGKKYRASKLGLAR |
| Sequence (3 Letter) | H - Trp - Trp - Gly - Lys - Lys - Tyr - Arg - Ala - Ser - Lys - Leu - Gly - Leu - Ala - Arg - OH |
| Molecular Weight | 1820.2 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
1, Proctor LM et al. Intl Immunopharmacol. 9, 800-806 (2009).
2, Ames, R. et al. Immunopharmacol. 38, 87 (1997).
2, Ames, R. et al. Immunopharmacol. 38, 87 (1997).
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