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Caspase 1 (ICE) Substrate 3f, fluorogenic
Ac - WEHD - AFC
| Overview | |
|---|---|
| Description | AFC (7-amino-4-trifluoromethylcoumarin)-derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AFC peptides by caspases generate strongly fluorescent AFC that is monitored fluorimetrically at 500-510 nm with excitation of 370-390 nm.Caspase-1 substrate |
| Sequence | Ac-WEHD-AFC |
| Sequence (3 Letter) | Ac - Trp - Glu - His - Asp - AFC |
| Molecular Weight | 838.6 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C desiccated and protected from light |
1, Gurtu V, et al. Anal Biochem 251, 98-102 (1997).; 2. Martins LM, et al. J Biol Chem 272, 7421-30 (1997).; 3. Deveraux QL, et al. Nature 388, 300-4 (1997).; 4. Xiang J, et al. Proc Natl Acad Sci USA 93, 14559-63 (1996).
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InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.