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LEAP - 1, Hepcidin, human
DTHFPICIFCCGCCHRSKCGMCCKT (Disulfide bridges: 7 - 23, 10 - 13, 11 - 19, 14 - 22)
| Overview | |
|---|---|
| Description | This 25 amino acid residues Liver-Expressed Antimicrobial Peptide 1 (LEAP-1) is also known as hepcidin. LEAP-1 is a liver-specific peptide, but may be detected in the heart and brain at a lesser amount. |
| Sequence | DTHFPICIFCCGCCHRSKCGMCCKT (Disulfide bridges: 7-23, 10-13, 11-19, 14-22) |
| Sequence (3 Letter) | H - Asp - Thr - His - Phe - Pro - Ile - Cys - Ile - Phe - Cys - Cys - Gly - Cys - Cys - His - Arg - Ser - Lys - Cys - Gly - Met - Cys - Cys - Lys - Thr - OH (Disulfide bridges: 7 - 23, 10 - 13, 11 - 19, 14 - 22) |
| Molecular Weight | 2789.5 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Krause, A. et al. Prot. Sci. 12, 143 (2003), Kluver, E. et al. J. Pept. Res. 59, 241(2002), Hunter, H. et al . J. Biol. Chem. 277, 37597 (2002).
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