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Noxa BH3, Peptide 1
| Overview | |
|---|---|
| Description | This peptide belongs to the Bcl-2 family of proteins. Noxa gene encodes a Bcl-2 homology 3 (BH3)-only member of this family; it contains the BH3 region, not other BH domains. When ectopically expressed, Noxa undergoes BH3 motif-dependent localization to mitochondria, it interacts with anti-apoptotic Bcl-2 family members resulting in the activation of caspase-9. |
| Sequence | PAELEVECATQLRRFGDKLNFRQKLL |
| Sequence (3 Letter) | H-Pro-Ala-Glu-Leu-Glu-Val-Glu-Cys-Ala-Thr-Gln-Leu-Arg-Arg-Phe-Gly-Asp-Lys-Leu-Asn-Phe-Arg-Gln-Lys-Leu-Leu-OH |
| Molecular Weight | 3075.6 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Oda, E. et al. Science 288, 1053 (2000).
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