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Bak BH3 (69 - 93)
| Overview | |
|---|---|
| Description | This peptide belongs to the functional domain of BAK, the member of the Bcl-2 family. Bak promotes apoptosis and binds anti-apoptotic family members including Bcl-2 and Bcl-xL. This domain in Bakt is necessary and sufficient for cytotoxic activity and binding to Bcl-xL. It is capable of modulating apoptosis in cells. |
| Sequence | STMGQVGRQLAIIGDDINRRYDSEF |
| Sequence (3 Letter) | H-Ser-Thr-Met-Gly-Gln-Val-Gly-Arg-Gln-Leu-Ala-Ile-Ile-Gly-Asp-Asp-Ile-Asn-Arg-Arg-Tyr-Asp-Ser-Glu-Phe-OH |
| Molecular Weight | 2842.2 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Chittenden, T. et al. EMBO J. 14, 5589 (1995).
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