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NRC - 13 Pleurocidin
| Overview | |
|---|---|
| Description | This antimicrobial peptide is designated as NRC-13, a variant of Pleurocidin isolated from the American plaice. The sequence of NRC-3 is derived based on conserved flanking regions of Pleurocidin: an N-terminal signal peptide and a C-terminal acidic peptide. NRC-13 is effective against many Gram-positive and Gram-negative pathogens, and highly effective against P. aeruginosa. |
| Sequence | GWRTLLKKAEVKTVGKLALKHYL-NH2 |
| Sequence (3 Letter) | H-Gly-Trp-Arg-Thr-Leu-Leu-Lys-Lys-Ala-Glu-Val-Lys-Thr-Val-Gly-Lys-Leu-Ala-Leu-Lys-His-Tyr-Leu-NH2 |
| Molecular Weight | 2652.3 |
| Properties | |
| Purity | > 95% By HPLC |
| Storage | Store at -20 °C, cap vial tightly at all times. |
Patrzykat, A. et al. Antimicrob Agents Chemother 47, 2464 (2003).
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