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FN - A208 Fusion Peptide
GRGDSGAASIKVAVSADR
| Overview | |
|---|---|
| Description | This peptide is a fusion of A208, derived from murine laminin a1, and the active site of fibronectin (GRGDS), with a glycine spacer. This peptide forms amyloid-like fibrils and promotes formation of actin stress fibers that mediate fibroblast cell attachment, offering it potential as a bioadhesive for tissue regeneration and engineering. FN-A208 interacts with IKVAV receptors and integrins. Its activity is disrupted by the presence of EDTA. |
| Sequence | GRGDSGAASIKVAVSADR |
| Sequence (3 Letter) | H - Gly - Arg - Gly - Asp - Ser - Gly - Ala - Ala - Ser - Ile - Lys - Val - Ala - Val - Ser - Ala - Asp - Arg - OH |
| Molecular Weight | 1716.9 |
| Properties | |
| Purity | % Peak Area By HPLC ≥ 95% |
| Storage | -20 °C |
Ohga, Y. et al. Biomater. 30, 6731 (2009). Kasai, S. et al. Biopolymers Pept. Sci. 76, 27 (2004).
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