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| Overview | |
|---|---|
| Synonyms | L-Pyroglutamyl-L-histidyl-L-prolinamideThyroliberin | 
| Description | Thyrotropin-releasing hormone (TRH) is a tripeptide hormone secreted by the hypothalamus that stimulates the release of thyrotropin. This tripeptide is involved in the regulation of the hypothalamic pituitary-thyroid axis; it stimulates the synthesis and release from the anterior pituitary of thyrotropin (TSH) and prolactin. | 
| Cas No | 24305-27-9 | 
| Sequence | {pGLU}{HIS}{PRO}-NH2 | 
| Sequence Shortening | pEHP-NH2 | 
| Molecular Formula | C16H22N6O4 | 
| C Terminal | NH2 | 
| Molecular Weight | 362.38 | 
| Properties | |
| Purity | > 95% | 
| Solubility | The peptide is soluble in water to 10 mg/ml, appearing clear and colorless. | 
| Gmp Flag | 0 | 
| Storage | Store the peptide at -20°C. Keep container tightly closed. | 
| Note | TRH and phorbol esters stimulate sphingomyelin synthesis in GH3 pituitary cells. | 
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