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Substance P (1-9)
| Overview | |
|---|---|
| Description | Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons. Substance P contracts smooth muscle, constricts bronchioles and increases capillary permeability. When released from afferent nerves, Substance P causes a neurogenic inflammatory response, including mast cell degranulation. NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; putative neurotransmitter in sensory (pain) afferents. Substance P(1-9) is a fragment of Subtance P. Accumulating evidence shows that N- and C-terminal substance P fragments have significant biological activity. Substance P(1-9) has been reported to be major substance P metabolites in rat striatum and it has modulatory effects similar to substance P. |
| Cas No | 57468-17-4 |
| Sequence | {ARG}{PRO}{LYS}{PRO}{GLN}{GLN}{PHE}{PHE}{GLY} |
| Sequence Shortening | RPKPQQFFG |
| Molecular Formula | C52H77N15O12 |
| Molecular Weight | 1104.3 |
| Properties | |
| Purity | > 95% |
| Gmp Flag | 0 |
| Storage | Store at -20°C。 |
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