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Overview | |
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Synonyms | ParasinI; Parasin 1; Parasin1 |
Description | Parasin I is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus). Eighteen of the 19 residues in parasin I are identical to the N-terminus of buforin I, a 39-residue antimicrobial peptide derived from the N-terminus of toad histone H2A. This implies that parasin I is cleaved off of the N-terminus of catfish histone H2A. Parasin I shows strong antimicrobial activity, about 12-100 times as strong as magainin 2, against a wide spectrum of microorganisms, without any hemolytic activity. Furthermore, parasin I shows good antimicrobial activity against fish-specific bacterial pathogens. |
Sequence | {LYS}{GLY}{ARG}{GLY}{LYS}{GLN}{GLY}{GLY}{LYS}{VAL}{ARG}{ALA}{LYS}{ALA}{LYS}{THR}{ARG}{SER}{SER} |
Sequence Shortening | KGRGKQGGKVRAKAKTRSS |
Molecular Formula | C82H154N34O24 |
Molecular Weight | 2000.3 |
Properties | |
Purity | > 95% |
Gmp Flag | 0 |
Storage | Store at -20°C |
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