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Overview | |
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Description | This hexapeptide corresponding to residues 42-47 of the thrombin receptor has been shown to be a thrombin receptor activator. It caused half-maximal platelet aggregation at approx. 0.8 uM and was 5 times more potent than the parent peptide H-8105. In addition, SFLLRN is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca2+. |
Sequence | {Ser}{Phe}{Leu}{Leu}{Arg}{Asn} |
Sequence Shortening | SFLLRN |
Molecular Formula | C34H56N10O9 |
Molecular Weight | 748.87 |
Properties | |
Purity | 95% |
Storage | Store at -20°C. |
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