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| Overview | |
|---|---|
| Synonyms | αMSH; a-MSH; aMSH; alpha-MSH; alphaMSH;α-Melanocyte Stimulating Hormone; αMelanocyte Stimulating Hormone; a-Melanocyte Stimulating Hormone; aMelanocyte Stimulating Hormone; alpha-Melanocyte Stimulating Hormone; alphaMelanocyte Stimulating Hormone; NDP-MSH[Nle4, D-Phe7]-α-MSH, amide |
| Description | [Nle4, DPhe7]-alpha-MSH (NDP-MSH), a highly potent analogue of alpha-melanocyte-stimulating hormone (alpha-MSH), possesses nanomolar efficacies at all the melanocortin receptor subtypes except the MC2R. Evaluation of the melanocortin 'message' sequence of [Nle4, DPhe7]-alpha-MSH was performed on the human melanocortin receptor subtypes designated hMC1, hMC3R, hMC4R, and hMC5R. |
| Cas No | 75921-69-6 |
| Sequence | Ac-{SER}{TYR}{SER}{NLE}{GLU}{HIS}{d-PHE}{ARG}{TRP}{GLY}{LYS}{PRO}{VAL}-NH2 |
| Sequence Shortening | Ac-SYSNleEHfRWGKPV-NH2 |
| Molecular Formula | C78H111N21O19 |
| C Terminal | NH2 |
| N Terminal | Ac |
| Molecular Weight | 1647.0 |
| Properties | |
| Purity | > 95% |
| Gmp Flag | 0 |
| Storage | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
| Note | [Nle4,DPhe7] alpha-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. [Nle4,DPhe7] alpha-MSH can affect inflammatory and immune responses and peripheral nerve regeneration. |
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