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| Overview | |
|---|---|
| Description | Substance P was found in the gut as well as in the brain. It is responsible for a number of excitatory effects on both central and peripheral neurons. Substance P contracts smooth muscle, constricts bronchioles and increases capillary permeability. When released from afferent nerves, Substance P causes a neurogenic inflammatory response, including mast cell degranulation. NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; putative neurotransmitter in sensory (pain) afferents. [Nle11]-Substance P is a Substance P analog that avoids methionine oxidation problems. | 
| Cas No | 57462-42-7 | 
| Sequence | {ARG}{PRO}{LYS}{PRO}{GLN}{GLN}{PHE}{PHE}{GLY}{LEU}{NLE}-NH2 | 
| Sequence Shortening | RPKPQQFFGL-Nle-NH2 | 
| Molecular Formula | C64H100N18O13 | 
| C Terminal | NH2 | 
| Molecular Weight | 1329.59 | 
| Properties | |
| Purity | > 95% | 
| Gmp Flag | 0 | 
| Storage | Store at -20°C. Keep tightly closed. Store in a cool dry place. | 
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