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Overview | |
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Description | Substance P was found in the gut as well as in the brain. It is responsible for a number of excitatory effects on both central and peripheral neurons. Substance P contracts smooth muscle, constricts bronchioles and increases capillary permeability. When released from afferent nerves, Substance P causes a neurogenic inflammatory response, including mast cell degranulation. NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; putative neurotransmitter in sensory (pain) afferents. [Nle11]-Substance P is a Substance P analog that avoids methionine oxidation problems. |
Cas No | 57462-42-7 |
Sequence | {ARG}{PRO}{LYS}{PRO}{GLN}{GLN}{PHE}{PHE}{GLY}{LEU}{NLE}-NH2 |
Sequence Shortening | RPKPQQFFGL-Nle-NH2 |
Molecular Formula | C64H100N18O13 |
C Terminal | NH2 |
Molecular Weight | 1329.59 |
Properties | |
Purity | > 95% |
Gmp Flag | 0 |
Storage | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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