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Overview | |
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Synonyms | NPY 13-36 |
Description | The C-terminal NPY fragment (13-36) [NPY-(13-36)], a Y2 receptor agonist, elicits vasopressor responses upon central administration. The cardiovascular responses of NPY-(13-36), together with the distribution of NPY receptor subtypes within the nucleus tractus solitarius (nTS), have been studied in spontaneously hypertensive rats (SHR). Neuropeptide Y (13-36) (NPY 13-36) stimulates both Y2 and Y5 NPY receptor subtypes, but causes no increase in food intake even when injected at high doses, while the full-length NPY is one of the most potent physiological stimulants of feeding yet described. NPY 13-16 inhibits retinotectal transfer in amphibians. |
Sequence | {PRO}{ALA}{GLU}{ASP}{MET}{ALA}{ARG}{TYR}{TYR}{SER}{ALA}{LEU}{ARG}{HIS}{TYR}{ILE}{ASN}{LEU}{ILE}{THR}{ARG}{GLN}{ARG}{TYR}-NH2 |
Sequence Shortening | PAEDMARYYSALRHYINLITRQRYNH2 |
Molecular Formula | C134H207N41O36S1 |
C Terminal | NH2 |
Molecular Weight | 3000.41 |
Properties | |
Purity | > 95% |
Gmp Flag | 0 |
Storage | Store the peptide at -20°C. |
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