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Neurokinin B
| Overview | |
|---|---|
| Synonyms | NKB |
| Description | Neurokinin B belongs to the tachykinin family. Neurokinin B may play an important role in the olfactory, gustatory, visceral, and neuroendocrine processing information. Neurokinin B is potent bronchioconstrictor and has neruomodulatory roles in various brain functions. Neurokinin B is a member of the tachykinin family of neuropeptides that also includes Substance P and Neurokinin A. These carboxyl terminal-amidated peptides are derived from two preprotachykinin genes - the PPT-A gene encodes the sequences of Substance P, Neurokinin A, and neuropeptide K and the PPT-B gene encodes the sequence of Neurokinin B. Neurokinin B stimulate the production of immunoglobulins in peripheral B lymphocytes, This conditional response to Neurokinin B is likely due NK-3 receptors present only following co-culture and activation. |
| Cas No | 86933-75-7 |
| Sequence | {ASP}{MET}{HIS}{ASP}{PHE}{PHE}{VAL}{GLY}{LEU}{MET}-NH2 |
| Sequence Shortening | DMHDFFVGLM-NH2 |
| Molecular Formula | C55H79N13O14S2 |
| C Terminal | NH2 |
| Molecular Weight | 1210.42 |
| Properties | |
| Purity | > 95% |
| Solubility | Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Gmp Flag | 0 |
| Storage | Store at -20°C. |
| Note | Novel mammalian Tachykinin in Porcine spinal cord. |
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