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Overview | |
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Synonyms | AcSDKP; Ac-S-D-K-P |
Description | Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. Acetyl Ser-Asp-Lys-Pro is also a specific substrate for the N-terminal active site of angiotensin-converting enzyme, which is responsible for its degradation in vivo. |
Cas No | 127103-11-1 |
Sequence | {SER}{ASP}{LYS}{PRO} |
Sequence Shortening | SDKP |
Molecular Formula | C20H33N5O9 |
N Terminal | AC |
Molecular Weight | 487.5 |
Properties | |
Purity | > 95% |
Gmp Flag | 0 |
Storage | Store at -20°C. |
Note | (CFU-S = Spleen Colony-Forming Units) N-Acetyl-Ser-Asp-Lys-Pro exerts a high inhibitory activity on the proliferation of hematopoietic pluripotent stem cells |
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