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Melittin
| Overview | |
|---|---|
| Description | This 26-residue polypeptide isolated from bee venom binds calmodulin in a Ca2+-dependent manner, activates phospholipase A2, and inhibits protein kinase C (IC50=5-7 mM) by binding to the catalytic domain in a Mg-ATP-sensitive manner. |
| Cas No | 20449-79-0 |
| Sequence | {GLY}{ILE}{GLY}{ALA}{VAL}{LEU}{LYS}{VAL}{LEU}{THR}{THR}{GLY}{LEU}{PRO}{ALA}{LEU}{ILE}{SER}{TRP}{ILE}{LYS}{ARG}{LYS}{ARG}{GLN}{GLN}-NH2 |
| Sequence Shortening | GIGAVLKVLTTGLPALISWIKRKRQQ-NH2 |
| Molecular Formula | C131H229N39O31 |
| C Terminal | NH2 |
| Molecular Weight | 2846.46 |
| Properties | |
| Purity | > 95% |
| Gmp Flag | 0 |
| Storage | Store at -20°C |
| Note | Polypeptide from honey bee venom |
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