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G3-C12
| Overview | |
|---|---|
| Description | Galectin-3 is a member of the galectin family of beta-galactoside-binding animal lectins. Galectin-3 is overexpressed in a wide range of neoplasms and is associated with tumor growth and metastases. Given this fact, radiolabeled galectin-3-targeting molecules may be useful for the noninvasive imaging of tumors expressing galectin-3, as well as for targeted radionuclide therapy. In this study, the tumor cell-targeting and SPECT properties of a galectin-3-avid peptide identified from bacteriophage display were evaluated in human breast carcinoma cells and in human breast tumor-bearing mice. The galectin-3-avid peptide G3-C12 (ANTPCGPYTHDCPVKR) was synthesized with a Gly-Ser-Gly (GSG) linker at the amino terminus. |
| Sequence | {Ala}{Asn}{Thr}{Pro}{Cys}{Gly}{Pro}{Tyr}{Thr}{His}{Asp}{Cys}{Pro}{Val}{Lys}{Arg} |
| Sequence Shortening | ANTPCGPYTHDCPVKR |
| Molecular Formula | C74H115N23O23S2 |
| Molecular Weight | 1758.98 |
| Properties | |
| Purity | >95% |
| Storage | Store at -20°C. |
About InnoPep
InnoPep Inc. is a company started by a couple of researchers with decades of expertise in peptide synthesis and conjugation aimed at enabling.